Cartilage Oligomeric Matrix Protein as New Marker in Diagnosis of Rheumatoid Arthritis
نویسندگان
چکیده
Rheumatoid arthritis (RA) is the most common systemic inflammatory autoimmune disease of unknown etiology. The early in diagnosis of RA is crucial. To facilitate diagnosis during the early stages of RA, when often not all clinical symptoms are manifest, a good serological marker is needed. Among serological markers are rheumatoid factor (RF), erythrocyte sedimentation rate (ESR) C-reactive protein (CRP), anti-cyclic citrullinated peptites (anti-CCP) and cartilage oligomeric matrix protein (COMP). A comparison between those markers in respect to the accuracy was the aim of this study.
منابع مشابه
Cartilage Oligomeric Matrix Protein (COMP): A Biomarker of Arthritis
Arthritis is a chronic disease with a significant impact on the population. It damages the cartilage, synovium, and bone of the joints causing pain, impairment, and disability in patients. Current methods for diagnosis of and monitoring the disease are only able to detect clinical manifestations of arthritis late in the process. However, with the recent onset of successful treatments for rheuma...
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This study aimed to evaluate the role of Anti-Cyclic Citrullinated Peptide (anti-CCP) antibody in comparison to Cartilage oligomeric matrix protein (COMP) in Rheumatoid Arthritis (RA) patients as predictors of the disease activity and cartilage destruction. The study included 60 patients &10 apparently healthy subjects. They were divided into 4 groups. Group 1: consisted of 20 patients with est...
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